Building tools for Complex Systems.

Open-Informatics builds tools that help human and artificial intelligence work with complexity across healthcare data, software delivery, and AI quality. We prioritize transparency, reproducibility, and practical utility.

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Healthcare Data MCP

ALPHA

18 MCP servers · 100 tools for public US healthcare intelligence

A FastMCP toolkit that turns scattered public sources — CMS, CDC, NIH, ClinicalTrials.gov, HHS OIG LEIE, SAM.gov, USAspending, CHPL, Census, HUD, BLS, SEC, IRS, OSRM, and hospital Machine-Readable Files — into focused local tools with structured responses, source metadata, and bounded caches.

18 Servers
100 Tools
v0.1.1 Release
cms-facility CMS facility master data and NPPES lookup search_facilities · search_npi
hospital-quality HCAHPS patient experience, HRRP readmissions, HAC safety get_readmission_data · get_safety_scores
drive-time OSRM + ORS isochrones for market & competitor analysis compute_drive_time_matrix · generate_isochrone
price-transparency Hospital Machine-Readable File index + negotiated rates get_negotiated_rates · benchmark_rates
claims-analytics Inpatient/Outpatient PUF volumes, service line trends, CMI get_inpatient_volumes · compute_case_mix
public-records SAM.gov, USAspending, CHPL, accreditation, 340B, HIPAA breaches, LEIE, and SAM exclusions search_usaspending · search_sam_exclusions
physician-referral-network DocGraph referral pairs, leakage detection, network mapping map_referral_network · detect_leakage
research-trials NIH RePORTER funding and ClinicalTrials.gov study activity profile_research_activity · search_clinical_trials
★ 6 stars ⚙ FastMCP 📦 v0.1.1 📅 Pushed Apr 2026 📁 MIT
MCP Python 3.11+ FastMCP CMS CDC SAM.gov Streamable HTTP Docker MIT

Companion data layer for agentic healthcare workflows: use stdio for local clients, local HTTP for shared processes, and the metadata-only gateway for remote MCP integrations.

GitHub →

Healthcare Admin Agents

LIVE

51 specialized AI agents for US healthcare administration

Portable prompt and SKILL.md pack for healthcare administration workflows. Installable across Claude Code, Codex, OpenCode, Cursor, Copilot, Windsurf, Gemini CLI, Cline, Amazon Q Developer, Continue.dev, and plain Markdown contexts.

51 Agents
10 Divisions
23K+ Lines
🏥
Strategy & Advisory 5 agents
🩹
Clinical Operations 8 agents
✅
Quality, Safety & Compliance 7 agents
💰
Revenue Cycle & Finance 6 agents
📄
Payer & Managed Care 6 agents
🌏
Population Health 3 agents
💻
Health IT & Informatics 6 agents
🏛
Operations & Admin 7 agents
💊
Pharmacy & Drug Programs 2 agents
🚨
Emergency Preparedness 1 agent
Claude Code Codex OpenCode Cursor v1.1.2 Healthcare AI Agents Apache 2.0
Healthcare Admin Agents - 51 specialized AI agents for US healthcare administration. | Product Hunt GitHub →

Systems Engineering

BETA

AI-native MBSE for safety-critical systems

Two open-source tools that turn agentic coding assistants into systems-engineering collaborators. A live MCP bridge into CATIA Magic / Cameo for real SysML and UML model manipulation, plus clause-level domain agents for ARP4754A, ISO 26262, IEC 62304, DO-254, and DoDAF. Real model edits, real matrices, real reviewer attack surfaces.

cameo-mcp-bridge v2.3.4

Open-source MCP bridge that lets MCP-compatible clients query, create, modify, and visualize SysML/UML models inside a running Cameo instance. A Python MCP server proxies to a Java plugin on 127.0.0.1:18740 and dispatches mutating operations on the Swing EDT inside SessionManager.

  • 46 README-documented tools across sessions, elements, diagrams, matrices, specs, macros, validation, and remediation
  • 18 diagram types (BDD, IBD, Sequence, StateMachine, Parametric, Requirement) with auto-layout + PNG export
  • Native SysML refine, derive, satisfy, and allocation matrices with row, column, and cell readback
  • Semantic validation for activity flow, port/interface boundaries, requirement quality, and cross-diagram traceability
  • OOSEM methodology packs, proofing helpers, auto-remediation previews, and review-package assembly
  • Groovy macro escape hatch; capability negotiation enforces plugin/server version lockstep
★ 10 stars ✓ 152 tests Python 63% · Java 36% MIT
View on GitHub →

mbse-agents v1.1.0

Five clause-level domain-expert agents — 3,291 lines of standards-indexed expertise with element-by-element crosswalks across Capella, Cameo, Rhapsody, Sparx EA, DOORS, and Simulink. Includes “reviewer attack surfaces” for DER, DAES, and FDA premarket inspections.

  • Aerospace SE — ARP4754A, ARP4761A, DO-178C/254, DO-326A/356A (673 lines)
  • Defense SE — DoDAF/UAF, MIL-STD-882E, DI-SESS, JCIDS (674 lines)
  • Automotive SE — ISO 26262, ISO 21434, ISO 21448 SOTIF, AUTOSAR (653 lines)
  • Medical Device SE — IEC 62304, ISO 14971, FDA QMSR, EU MDR 2017/745 (687 lines)
  • Electronic Systems SE — DO-254, IEC 61508, IEEE 1800/1076, AEC-Q100 (604 lines)
  • 20 reference example systems (FMS, UAS GCS, AEB, infusion pump, quantum processor)
★ 4 stars 5 agents 3,291 lines 30+ standards MIT
View on GitHub →
MBSE SysML Cameo Capella DO-178C ISO 26262 IEC 62304 MCP

Install either in 30 seconds — ./install.sh for the Cameo bridge or cp mbse-agents/agents/*.md ~/.claude/agents/ for the domain experts.

AJHCS.org

LIVE

Where Strategy, Meets Evidence

The American Journal of Healthcare Strategy — evidence-based insights trusted by 13,000+ healthcare leaders. Open-access peer review with a 2–3 week turnaround, three original podcast formats, and a bookstore publishing Open-Informatics’ health system data reports.

13K+ Subscribers
500K Monthly Impressions
200+ Podcast Episodes
150+ Experts
AJHCS.org homepage — Where Strategy, Meets Evidence
ajhcs.org
Publications
Peer-reviewed, open access. 2–3 week review. Inline article annotations for researcher-grade margin commentary.
Podcast Network
3 original formats: The Strategy of Health, Clinicians in Leadership, The Fellowship Review. ~1K downloads per episode.
Bookstore
The Administrative Fellowship Guide ($24.99). Jefferson Health System Data Report, March 2026 edition — 91 pages, $99.

Designed by Open-Informatics in Philadelphia. Published pro bono.

Visit Site →
United States Health Systems Observatory seal
United States Health Systems Observatory

Illuminating how U.S. health systems act and adapt

The Observatory produces comprehensive intelligence reports on the financial health, quality outcomes, market position, and strategic direction of major U.S. health systems. Each report synthesizes public filings, CMS data, and competitive analysis into a single reference document.

Financial Performance Operating margins, cash flow, bond ratings, payer mix, and capital allocation — sourced from audited IRS Form 990s and MSRB bond disclosures.
Quality & Outcomes HCAHPS, HRRP readmissions, HAC safety scores, and CMS Star Ratings — benchmarked against national and peer-cohort performance.
Market Position Service-area share, commercial mix, inpatient and outpatient volumes, drive-time competitive analysis, and physician referral flows.
Strategic Direction Leadership succession, M&A activity, service-line investments, joint ventures, and public strategic commitments.
Unlimited Access $99 / year Every current and future system report. Students get free access.
Currently Covering
Jefferson Health Temple Health … and growing
New U.S. health systems are added on a rolling basis; every existing report is kept current.

A single subscription to the Observatory — available through the AJHCS Bookstore.

Browse Reports →